Alphadol 0.25mg Capsule

Alphadol 0.25mg Capsule is a prescription oral supplement that belongs to the class of vitamin D analogs. It is primarily used in the management of calcium metabolism disorders, including chronic kidney disease (CKD)-related bone disease, hypocalcemia, rickets, and osteomalacia. Alfacalcidol is a synthetic analog of vitamin D3, which becomes active in the liver without requiring renal conversion—making it suitable for patients with impaired kidney function.

Vitamin D plays a critical role in regulating calcium and phosphate levels, essential for strong bones and teeth, proper muscle function, and overall metabolic balance. Unlike cholecalciferol (inactive vitamin D3), Alfacalcidol is a fast-acting prodrug that bypasses renal activation, offering faster therapeutic effects in vitamin D–deficient states.

Alphadol 0.25mg Capsule is commonly prescribed for:

• Renal osteodystrophy

• Secondary hyperparathyroidism

• Hypocalcemia in chronic kidney disease

• Vitamin D–resistant rickets

• Postmenopausal or senile osteoporosis (off-label)