Latofix Eye Drops (Latanoprost 0.005% w/v) is a topical ophthalmic solution used to reduce elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It contains Latanoprost, a prostaglandin analog, which works by increasing the outflow of aqueous humor from the eye, thereby lowering pressure inside the eye.
Product Description:
- Active Ingredient: Latanoprost 0.005% w/v (50 micrograms per mL).
- Therapeutic Use: Indicated for the treatment of open-angle glaucoma and ocular hypertension in adults to reduce intraocular pressure, which can help prevent damage to the optic nerve and vision loss.
- Mechanism of Action: Latanoprost mimics prostaglandins, increasing the uveoscleral outflow of aqueous fluid from the eye, thus reducing IOP.
- Formulation: Sterile eye drop solution, typically supplied in a 2.5 mL bottle.
- Preservative: Contains benzalkonium chloride, a common preservative in ophthalmic products, which may be absorbed by soft contact lenses and cause irritation in some patients.
- Dosage and Administration:
- Usually one drop in the affected eye(s) once daily, preferably in the evening.
- Contact lenses should be removed before instillation and may be reinserted after 15 minutes.
- Side Effects:
- Common: Blurred vision, red eye, irritation, pain, or increased pigmentation of the iris (may cause eye color change).
- Less common: Eyelash changes (increased length, thickness, or number), eyelid skin darkening, or dry eyes.
- Contraindications: Hypersensitivity to Latanoprost, benzalkonium chloride, or any component of the formulation.
- Precautions:
- Use with caution in patients with a history of intraocular inflammation (e.g., uveitis) or macular edema.
- May cause gradual, permanent changes in eye color or eyelash appearance.
- Not recommended for use in children unless specifically advised by a healthcare provider.
- Storage: Store at 2–8°C (refrigerated) before opening; after opening, it can be stored at room temperature (below 25°C) for up to 4 weeks.