Mebrest Plus Tablet

Mebrest Plus Tablet is a combination medicine used for the treatment of Irritable Bowel Syndrome (IBS), intestinal spasms, abdominal pain, bloating, and stress-related gastrointestinal disorders. It contains Mebeverine, an antispasmodic that relaxes the smooth muscles of the intestine to relieve painful bowel spasms, and Chlordiazepoxide, a benzodiazepine that reduces anxiety and stress, which can worsen digestive symptoms. The combination helps relieve abdominal cramps, pain, bloating, discomfort, and irregular bowel movements, especially in patients whose symptoms are triggered or aggravated by emotional stress. Mebrest Plus improves bowel comfort without significantly affecting normal intestinal movement. Because it contains Chlordiazepoxide, it should be used only for the prescribed duration to reduce the risk of dependence. The medicine should always be taken under the supervision of a healthcare professional.

Mebrest Plus Tablet combines Mebeverine 135 mg and Chlordiazepoxide 5 mg to provide effective relief from Irritable Bowel Syndrome (IBS) and stress-related gastrointestinal disorders. Mebeverine is a selective antispasmodic that relaxes the smooth muscles of the gastrointestinal tract, relieving painful bowel spasms, abdominal cramps, bloating, and discomfort without significantly interfering with normal intestinal motility. Chlordiazepoxide, a benzodiazepine, reduces anxiety and emotional stress by enhancing the activity of gamma-aminobutyric acid (GABA) in the brain. Since emotional stress often worsens IBS symptoms, controlling anxiety helps reduce digestive disturbances. The combination addresses both the physical intestinal spasms and the psychological factors contributing to gastrointestinal discomfort.

Regular use as prescribed improves bowel comfort, reduces abdominal pain, and enhances quality of life. Because Chlordiazepoxide may cause dependence with prolonged use, treatment should be limited to the prescribed duration and discontinued gradually under medical supervision when necessary.

Precaution

• May cause drowsiness or dizziness; avoid driving or operating machinery.
• Do not consume alcohol, as it increases the sedative effect.
• Inform your doctor if you have liver disease, kidney disease, glaucoma, respiratory disorders, or a history of substance misuse.
• Use cautiously in elderly patients due to an increased risk of falls and confusion.
• Avoid prolonged use because Chlordiazepoxide may cause dependence.
• Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Storage

• Store below 30°C in a cool, dry place.
• Protect from moisture and direct sunlight.
• Keep the tablets in the original packaging.
• Keep out of reach of children.
• Do not use after the expiry date.