Valcutril 100mg Tablet

Valcutril 100 mg Tablet is a prescription medicine used for the treatment of chronic heart failure with reduced ejection fraction (HFrEF). It contains Sacubitril, a neprilysin inhibitor, and Valsartan, an angiotensin II receptor blocker (ARB), which work together to improve heart function and reduce the workload on the heart. This combination helps the heart pump blood more efficiently, lowers blood pressure, reduces fluid buildup, and decreases the risk of hospitalization due to heart failure and cardiovascular death. It also helps relieve symptoms such as shortness of breath, fatigue, swelling of the legs, and reduced exercise tolerance. Valcutril 100 mg is usually prescribed for long-term management of heart failure and should be taken regularly along with lifestyle changes, including a low-salt diet, regular exercise as advised, fluid management, and routine follow-up with your healthcare provider for the best treatment outcomes.

Valcutril 100 mg Tablet combines Sacubitril 49 mg and Valsartan 51 mg to provide effective treatment for chronic heart failure with reduced ejection fraction. Sacubitril inhibits the enzyme neprilysin, increasing beneficial natriuretic peptides that relax blood vessels, promote the removal of excess sodium and water, reduce fluid overload, and decrease pressure on the heart. Valsartan, an angiotensin II receptor blocker, prevents blood vessel narrowing and blocks hormones that contribute to high blood pressure and fluid retention. Together, these medicines improve cardiac output, reduce symptoms such as breathlessness, fatigue, and swelling, and significantly lower the risk of hospitalization and cardiovascular death.

Long-term therapy helps slow the progression of heart failure while improving exercise tolerance and daily functioning. Combined with healthy lifestyle practices, including limiting dietary salt, taking medications regularly, maintaining a healthy weight, and attending routine medical check-ups, Valcutril supports better heart health and enhances long-term quality of life.

Precaution

• Use only under medical supervision.
• Do not use during pregnancy, as it can seriously harm the unborn baby.
• Inform your doctor if you have kidney disease, liver disease, or low blood pressure.
• Avoid potassium supplements or potassium-containing salt substitutes unless advised.
• Regular monitoring of blood pressure, kidney function, and potassium levels may be required.
• Do not take with an ACE inhibitor within 36 hours, as this increases the risk of angioedema.

Storage

• Store below 30°C.
• Keep in a cool, dry place.
• Protect from moisture and direct sunlight.
• Store in the original packaging.
• Keep out of reach of children.